Pharmacel® sMCC 90

Pharmacel® sMCC 90, a silicified microcrystalline cellulose, developed as the synergistic solution for challenging oral solid dosage formulations. Co-processing microcrystalline cellulose with silicon dioxide increases its surface area, resulting in enhanced powder flow, superior tabletability, and improved formulation robustness.

Pharmacel® sMCC 90 benefits

This new addition to our well-established excipients’ portfolio offers customers worldwide the highest quality excipients and services. Pharmacel® sMCC 90 has the following benefits compared to conventional excipients:

- Improved tablet compression

- Higher production speeds

- Rapid formulation development

Improved tablet compression

Pharmacel® sMCC 90 is a highly functional excipient for direct compression processes. In comparison with conventional excipients, Pharmacel® sMCC 90 leads to lower capping of tablets at high compaction speed thereby enabling 20% harder tablets.

Higher production speeds

The production speed of tablets depends on the pace of several intermittent steps. Pharmacel® sMCC 90 enables higher processing speed in n multiple units of operation. Additionally, Pharmacel® sMCC 90 allows for a swift and more consistent flow from the hopper.

The flowability of Pharmacel® sMCC 90 enables consistency in tablet weight, with weight variation below 1% for 250mg placebo tablets.

Rapid formulation development

Pharmacel® sMCC 90 mitigates formulation challenges due to its improved flow and compaction compared to conventional excipients. Additionally, low lubricant and dwell-time sensitivity allow for easy-scale up. Moreover, Pharmacel® sMCC 90 reduces the number of excipients compared to regular grades and removes the need to process

Particle size distribution (μm)
X10: 35
X50: 110
X90: 270

Bulk density (g/L)
318

Hausner ratio (-)
1.46

LOD (% w/w)
4.4

Download full product specifications: https://dfepharma.mastercontrol.com/dfepharma/main/index.cfm?event=showFile&ID=AAWCRON7YFDN7H7X7Y&static=false&mcuid=ANONYMOUS&mcsid=3RDNWWTMXVG3TMXUXC

Expected delivery within 5-7 days. Each order ships with Certificate of Analysis, Material Safety Data Sheet and Product Data Sheet.