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Pharmacel® sMCC 90

Pharmacel® sMCC 90

Silicified microcrystalline cellulose

Pharmacel® sMCC 90, a silicified microcrystalline cellulose, developed as the synergistic solution for challenging oral solid dosage formulations. Co-processing microcrystalline cellulose with silicon dioxide increases its surface area, resulting in enhanced powder flow, superior tabletability, and improved formulation robustness.

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Benefits

Pharmacel® sMCC 90 has the following benefits compared to conventional excipients:

Improved tablet compression
Pharmacel® sMCC 90 is a highly functional excipient for direct compression processes. In comparison with conventional excipients, Pharmacel® sMCC 90 leads to lower capping of tablets at high compaction speed thereby enabling 20% harder tablets.

Higher production speeds
The production speed of tablets depends on the pace of several intermittent steps. Pharmacel® sMCC 90 enables higher processing speed in n multiple units of operation. Additionally, Pharmacel® sMCC 90 allows for a swift and more consistent flow from the hopper.

The flowability of Pharmacel® sMCC 90 enables consistency in tablet weight, with weight variation below 1% for 250mg placebo tablets.

Rapid formulation development
Pharmacel® sMCC 90 mitigates formulation challenges due to its improved flow and compaction compared to conventional excipients. Additionally, low lubricant and dwell-time sensitivity allow for easy-scale up. Moreover, Pharmacel® sMCC 90 reduces the number of excipients compared to regular grades and removes the need to process

Typical product data

Particle size distribution (μm)
Method: by dry laser diffraction
X10: 35
X50: 110
X90: 270

Bulk density (g/L): 318
Hausner ratio (-): 1.46
LOD (% w/w): 4.4

Product specifications

Download full product specifications: https://dfepharma.mastercontrol.com/dfepharma/main/index.cfm?event=showFile&ID=AAWCRON7YFDN7H7X7Y&static=false&mcuid=ANONYMOUS&mcsid=3RDNWWTMXVG3TMXUXC

Quality

Complies with USP-NF, JPE
Kosher & Halal certified

Packaging

Capacity: 25kg
Composition: Multi-layer PE
Shelf life: 24 months retest

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Unit price $24.69  per kg
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