Lactohale® 206
Lactohale® 206
Lactohale® 206 is a coarse milled alpha lactose monohydrate grade where the fine lactose particles have been removed. The coarse milled lactose grade could be used as a basic lactose grade in applications where a good flow is required. Mixing this coarse grade with fine lactose provides formulators a means to optimize flow and deposition of a Dry Powder Inhalation blend.
Product description
Product description
Lactohale® 206 is a coarse milled alpha lactose monohydrate grade where the fine lactose particles have been removed. The coarse milled lactose grade could be used as a basic lactose grade in applications where a good flow is required. Mixing this coarse grade with fine lactose provides formulators a means to optimize flow and deposition of a Dry Powder Inhalation blend. Different types of fines are available for this optimization, being Lactohale® 210, Lactohale® 220, Lactohale® 230 and Lactohale® 300. Blending with very fine lactose grades typically has a significant impact on the drug deposition. Adding slightly coarser fines, like Lactohale® 210, mainly has an impact on the powder cohesiveness, with limited impact on deposition.
At DFE Pharma a wide range of milled and sieved inhalation lactose grades are available referred to as Lactohale® and Respitose®. Customers typically start their development with Lactohale® DoE products, and they can convert to customization to fine-tune the performance of their formulation. In close collaboration, the flow properties can be matched to the correct fines content for an optimal product performance. The resulting Customized Lactohale® grade with their specific particle size profiles is unique for each customer.
Typical product data
Typical product data
Particle size distribution (μm)
D10
33
D50
83
D90
154
Bulk density (g/L)
720
Tapped density (g/L)
870
Carr’s index (-)
17
Product specifications
Product specifications
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Packaging
Packaging
20 kg Cartonboard box NL (ALU/PE liner)
Product delivery
Product delivery
Each order ships with Certificate of Analysis, Material Safety Data Sheet and Product Data Sheet.