Lactohale® 206

Lactohale® 206 is a coarse milled alpha lactose monohydrate grade where the fine lactose particles have been removed. The coarse milled lactose grade could be used as a basic lactose grade in applications where a good flow is required. Mixing this coarse grade with fine lactose provides formulators a means to optimize flow and deposition of a Dry Powder Inhalation blend. Different types of fines are available for this optimization, being Lactohale® 210, Lactohale® 220, Lactohale® 230 and Lactohale® 300. Blending with very fine lactose grades typically has a significant impact on the drug deposition. Adding slightly coarser fines, like Lactohale® 210, mainly has an impact on the powder cohesiveness, with limited impact on deposition.

At DFE Pharma a wide range of milled and sieved inhalation lactose grades are available referred to as Lactohale® and Respitose®. Customers typically start their development with Lactohale® DoE products, and they can convert to customization to fine-tune the performance of their formulation. In close collaboration, the flow properties can be matched to the correct fines content for an optimal product performance. The resulting Customized Lactohale® grade with their specific particle size profiles is unique for each customer.

Particle size distribution (μm)
D10
33

D50
83

D90
154

Bulk density (g/L)
720

Tapped density (g/L)
870

Carr’s index (-)
17

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20 kg Cartonboard box NL (ALU/PE liner)

Each order ships with Certificate of Analysis, Material Safety Data Sheet and Product Data Sheet.